Kin Therapeutics applies the most advanced biopharmaceutical strategies to treat connective tissue diseasesConnective tissue disorders include several genetic diseases impacting the extracellular matrix and bone. There are over 200 heritable disorders of connective tissue. One area of focus is the rare genetic disorder called Ehlers Danlos (classical and vascular types). People with Ehlers Danlos have mutations in Collagen that cause joint hypermobility, skin defects, vascular and soft tissue abnormalities and even early death. Other genetic diseases of connective tissue that we study include Marfan Syndrome and Osteogenesis Imperfecta. The extracellular matrix plays a vital role in many bone and connective tissues disorders, cardiovascular disease, and dermatological conditions. More common types of connective tissue disorders include rheumatoid arthritis, firbromyalgia, scleroderma, and lupus. Our research and drug development efforts aim to find solutions for these debilitating conditions.